Retin-A (tretinoin topical) is a form of vitamin A that you are supposed to apply to you skin. This medicine is used or faster skin renewal to treat such conditions as acne, although other brands containing the same active ingredients are also use for other skin conditions. Use Retin-A exactly as recommended and talk to your health care provider and make sure you report the fact of having no improvement in the condition of your acne after 12 weeks of applying it regularly. Make sure you do not skip applications or miss them too often, as this will affect your result directly. Some mild side effects are possible when taking Retin-A, and can include such symptoms as stinging, tingling, itching, irritation, skin discoloration, burning, warmth, swelling, peeling, dryness, and redness. If those symptoms continue for several days you may want to talk to your health care provider about making a small pause for your skin to regain its normal condition. However, always consult your doctor before doing anything about the condition of your skin. Some drugs you may be taking can interact with Retin-A and make your skin even more sensitive to sunlight, so make sure you report them fact of taking any of the following drugs to your health care provider: antibiotics, sulfa drugs, diuretics, chlorpromazine, or fluphenazine.